Cat. No. ARC1035
Cancer (Tumor) Cell Lines
Homo sapiens (Human)
Blood (peripheral blood)
Burkitt lymphoma
The BJAB cell line is a human Burkitt lymphoma cell line (B cell orgin), derived from the inguinal tumor of a 5-year-old African girl. It is an Epstein-Barr virus (EBV)-negative lymphoblastoid cell line that does not harbor EBV genome or express EBV specified antigen EBNA, but these cells carry surface-bound immunoglobulin. BJAB grows in suspension with a round to polymorphic morphology. The cells rapidly lose viability when approaching maximal culture density; therefore, over-dense cultures should be avoided.
BJAB has wide applications in molecular mechanism and cancer research. Their stable EBV status allows for a valuable application in research on EBV transformation or infection of B cells, enabling researchers to investigate the effect of EBV virus contributing to lymphomagenesis. Otherwise, the BJAB cells exhibit features of Burkitt lymphoma, making it a cell model for genetic and phenotypic studies. The BJAB cell line also serves as a cell model of EBV-negative Burkitt lymphoma in biomedical research for evaluating cytotoxic activity in comparison with EBV-positive counterparts.
Synonyms: BJAb; BJA-B; BJAB-1; BJA-B1; BJA-B-1
Cryopreserved in vials and shipped on dry ice
Characteristics
Cell Type
B cell line
Sex of Donor
Female
Age
5 years
Derived From Site
In situ; Groin
Growth Mode
Suspension
Morphology
Round to polymorphic cells
Culture Conditions
Temperature
37℃
Atmosphere
5% CO2
Quality Control
Sterility testing
The bacterial, yeast, and fungi are not detected in these cells by daily monitor.
Mycoplasma testing
Negative for mycoplasma through PCR analysis
Disclaimer
Intended Use
This product is intended for laboratory in vitro use only. lt is not intended for diagnostic, therapeutic, or clinical applications.
Disclaimer
Ascent Research endeavors to provide accurate and up-to-date product information. However, no warranties or representations are made regarding its completeness or reliability. References to scientific literature and patents are for informational purposes only, and the customer assumes sole responsibility for verifying their accuracy.
By accepting this product, the customer acknowledges and agrees to assume all risks associated with its receipt, handling, storage, disposal, and use, including compliance with all applicable safety and environmental regulations and precautions. Relevant laws, regulations, and ethical guidelines must be followed in conducting any research, modifications, or derivatives derived from this product.
This product is provided "AS IS", and except as expressly stated herein, Ascent Research disclaims all other warranties, express or implied. Under no circumstances shall Ascent Research, its affiliates, or representatives be liable for indirect, incidental, consequential, or punitive damages arising from the use of this material. While Ascent Research employs rigorous quality control measures, we shall not be held responsible for damages resulting from misidentification or misinterpretation of the provided materials.
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