Cat. No. ARC1034
Cancer (Tumor) Cell Lines
Homo sapiens (Human)
Blood (peripheral blood)
Acute myeloid leukemia (AML)
The KO52 cell line was established from the bone marrow of a patient with multi-lineage CD7-positive acute leukemia. Under laboratory conditions, these cells expressed specific markers to identify its lineage, such as myeloid-associated antigens (CD13, CD14, and CD33) and lymphoid markers (CD2, CD5, and CD7), as well as HLA-DR. The KO52 carries mutations in p53 and N-ras gene, which are typically associated with different stages or subtypes of leukemia. When exposed to G-CSF, IL-2, PMA, or vitamin D3, KO52 cells might exhibit some characteristics of granulocytic or monocytic/macrophage-like differentiations.
Synonym: KO-52; K052; K-052
1 million
$700.00
In stock
Ships next business day
Cryopreserved in vials and shipped on dry ice
Characteristics
Sex of Donor
Male
Age
46 years
Derived From Site
In situ; Bone marrow
Growth Mode
Suspension
Morphology
Lymphocyte-like
Culture Conditions
Temperature
37℃
Atmosphere
5% CO2
Quality Control
Sterility testing
The bacterial, yeast, and fungi are not detected in these cells by daily monitor.
Mycoplasma testing
Negative for mycoplasma through PCR analysis
Disclaimer
Intended Use
This product is intended for laboratory in vitro use only. lt is not intended for diagnostic, therapeutic, or clinical applications.
Disclaimer
Ascent Research endeavors to provide accurate and up-to-date product information. However, no warranties or representations are made regarding its completeness or reliability. References to scientific literature and patents are for informational purposes only, and the customer assumes sole responsibility for verifying their accuracy.
By accepting this product, the customer acknowledges and agrees to assume all risks associated with its receipt, handling, storage, disposal, and use, including compliance with all applicable safety and environmental regulations and precautions. Relevant laws, regulations, and ethical guidelines must be followed in conducting any research, modifications, or derivatives derived from this product.
This product is provided "AS IS", and except as expressly stated herein, Ascent Research disclaims all other warranties, express or implied. Under no circumstances shall Ascent Research, its affiliates, or representatives be liable for indirect, incidental, consequential, or punitive damages arising from the use of this material. While Ascent Research employs rigorous quality control measures, we shall not be held responsible for damages resulting from misidentification or misinterpretation of the provided materials.
