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Case studies contain reports on ASCENT’s exploration of the underlying mechanisms of cell states, including cell growth, cell differentiation, and even cell death.
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Genome-edited Cells

Genome-edited cell lines are cells whose genome has been modified using genome editing tools such as CRISPR/Cas9, TALENs, and PiggyBac systems, introduced by plasmid transfection and viral transduction. The gene functions have been altered for specific research needs. These cell lines and alternatives are:

Knockin – Insertion of gene of interest (GOI) into a specific locus
Knockout – deletion or disruption of a target gene
Knockdown – suppression of gene expression
Overexpression – strongly promoting gene expression of a gene
Reporter Labeling – precisely or randomly introduce reporter gene to tag proteins or label cells.

These genome-edited stable cell lines are widely used in scientific research such as disease modelling, gene functional assay, pathway and mechanism assay, and drug screening.

Explore our genome-editing cell lines as follow, learn more about our Cell Line Development Service, or contact us to custom your own cell lines.

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