HEL-100 is a human cell line established from the breast milk of a healthy female donor with no family history of breast cancer. Although derived from the non-cancerous tissue, HEL-100 cells exhibit several features indicative of transformation. By the 7th passage, karyotype analysis revealed chromosomal abnormalities. Ultrastructural examination via electron microscopy showed the presence of microfilaments, tension fibrils, and desmosomes. It showed the integration of SV40 viral genes into the genome in southern blot analysis.
Daily monitoring confirms that the cells are free from bacterial, yeast, and fungal contamination.
Mycoplasma testing
Negative for mycoplasma through PCR analysis
Pathogens
Cells tested negative for HIV-1, HBV, and HCV.
Disclaimer
Intended Use
This product is intended for laboratory in vitro use only. lt is not intended for diagnostic, therapeutic, or clinical applications.
Disclaimer
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