Research on the Human Lymphatic Fibroblasts is essential to the study of regulating immune response and homeostasis of tissue fluids, lymphatic tissue fibrosis, chronic lymphedema progression, tumor stroma interactions in lymph nodes, and extracellular matrix remodeling in lymphatic diseases. Lymph nodes are bean-shaped organs of the lymphatic system, distributed throughout the body but clustered in the neck, armpits, and groin. They consist of a capsule, cortex, and medulla, and contain a large number of lymphocytes. Lymph nodes are important parts of the human immune system, with their primary functions being to filter lymphatic fluid, remove pathogens, and activate immune cells to fight infections. The Human Lymphatic Fibroblasts are to be used with Human Lymphatic Fibroblast Medium (Cat. No. ACM0072). This product is intended for laboratory in vitro use only. It is not intended for diagnostic, therapeutic, or clinical applications.